It’s been five years since we last saw Camille Cottin as Andréa Martel, the hard-charging and surprisingly vulnerable deal-maker whose droll comic timing anchored the France 2/Netflix series Call My Agent!. Now, Andréa is back and better than ever in Call My Agent! The Movie.

The film—which lands on Netflix September 10—finds Andréa making tentative inroads with some of her former colleagues at the Parisian talent agency ASK while trying to balance single motherhood and a burgeoning new career that has her desperately chasing stars like George Clooney for her directorial debut.

Vogue spoke to Cottin—who has also appeared opposite Lady Gaga and Adam Driver in House of Gucci, with Jodie Comer on Killing Eve, and, more recently, alongside Jamie Dornan and Michelle Yeoh in Kenneth Branagh’s A Haunting in Venice—about portraying Andréa’s personal and professional growth, French versus American global film distribution, and learning from some of the film’s megawatt guest stars.

Vogue: What’s the biggest difference between where we left Andréa on the show and where we meet her in the film?

Camille Cottin: Well, first of all, her child is six years old, right? So we’re talking about becoming a mother and all the things it implies.

For Andréa, I think having a child is probably her first love, because Andréa has always had a lot of difficulties engaging and she’s always scared of commitment. Her child is Andréa’s first life commitment and real love, and I think she’s exploring a lot of desires she has long denied herself.

How has Hollywood changed since you filmed the show’s finale just before the first COVID lockdowns?

Streaming platforms obviously have really spread and and become global phenomena. The success of the platform has grown incredibly.

When we were doing Call My Agent!, we were bought by Netflix, but when you work directly with the platform and they’re producing, it’s a different way of working. Netflix was an amazing partner and producer on the film and really gave us the means to to do the film we wanted to do.

The fact that the streaming platforms have extended their presence also gives an international echo to the work, which is pretty amazing. When you produce a French film at home for French cinema, obviously you hope for it to be sold abroad, but to have Call My Agent! released in 197 countries is not something we could have imagined or dreamed of.

I think Hollywood is used to having its films spread worldwide, but for us, it’s something very, very new.

Call My Agent! has always attracted amazing guest stars. What was it like working with Eva Longoria and George Clooney?

It was so great. We were all really happy to make this movie five years after the show had wrapped, but at the same time, you understand time has gone by, and you just wonder if if people will still be happy to be reunited with the characters.

The fact that George Clooney and Eva Longoria agreed to be part of the project was a beautiful way of encouraging us in doing this film and thinking of it as a kind of happy reunion. They’re both politically very engaged, and it was really lovely to see them come on set with such enthusiasm and such enlightened presences.

Everyone was charmed by them because both George and Eva have this spontaneity towards people they don’t know and this talent of making you feel at ease, and they’re very warm and talented. It was really a gift.

Which of Andréa’s former colleagues were you most excited to see her reunite with?

I was delighted to bring her back with Gabriel [Grégory Montel] and see them continue their adventures. The show ended in a pretty pessimistic way, with the agency being eaten up by the competitors and Andréa failing to maintain it.

Everybody was just living in their own directions and Gabriel was working for the competitors in a way that that made Andréa fiercely angry with him and no longer wanting to be his friend, and I was really happy that—I don’t want to spoil it, but—that we could we could repair that relationship. I was also really excited to work in duet with Laure Calamy, because during the previous seasons, we didn’t have the occasion to be side by side.

Those two women are so different, and they have such a different approach toward human relationships and cinema, that it was full of the promise of comedy to have them together.

Would you be up for continuing Andréa’s story from here?

Well, it’s a bit early to say this, but I would answer that Andréa is a beautiful character. She is a source of inspiration because she is a beautiful representative of the queer community in the way that she’s totally free and fearless and strong.

I think she’s very inspiring in terms of femininity, and she’s funny and full of flaws, and you hate her, but you adore her. I have an immense sympathy for that character.

It’s always a pleasure to be Andréa, and I don’t think I could get tired of being Andréa, because now she’s become a close friend.

This conversation has been edited and condensed.